Treatment of end stage dilated cardiomyopathy
نویسندگان
چکیده
منابع مشابه
Treatment of end stage dilated cardiomyopathy.
Patients should be referred for cardiac transplantation only after all other means of management of congestive heart failure have been attempted and have been unsuccessful (table 3). An adequate therapeutic trial of conventional and experimental agents including beta blockade and vesnarinone should be completed and be shown to be unsuccessful before transplantation is considered in patients in ...
متن کاملAutoimmune markers are undetectable in end stage idiopathic dilated cardiomyopathy.
BACKGROUND Autoreactive humoral and cellular immune responses may be involved in the pathogenesis of idiopathic dilated cardiomyopathy (IDC). Certain human leucocyte antigens (HLA) could also be linked to the development of IDC. AIM To determine whether various markers of autoimmunity are present in the final phase of the disease, to substantiate the role of an autoimmune process in IDC. ME...
متن کاملLeft ventricle restoration in end stage ischemic dilated cardiomyopathy
Background Patients with end stage dilated cardiomyopathy exhibit extensive remodeling of the left ventricle, annular dilation, and significant mitral and tricuspid regurgitation. These changes increase perioperative morbidity and mortality, and emphasize patient candidacy for heart transplantation. We previously published that Reductive Annuloplasty of Double (mitral and tricuspid) Orifices co...
متن کاملIdentification of micro-RNA networks in end-stage heart failure because of dilated cardiomyopathy
Micro-RNAs regulate gene expression by directly binding to the target mRNAs. The goal of the study was to examine the expression profiling of miRNAs in human failing hearts and identify the key miRNAs that regulate molecular signalling networks and thus contribute to this pathological process. The levels of miRNAs and expressed genes were analysed in myocardial biopsy samples from patients with...
متن کاملSix1 is down‐regulated in end‐stage human dilated cardiomyopathy independently of Ezh2
BACKGROUND Recently, it was shown that a knock-out (KO) of the polycomb histone methyltransferase Ezh2 leads to cardiac hypertrophy in mice, which was driven by the homeodomain transcription factor Six1. Here, we analyzed the expression of Six1 and its regulating factor Ezh2 in cardiac tissue of patients with end-stage dilative cardiomyopathy (DCM). METHODS Tissue samples of patients with end...
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ژورنال
عنوان ژورنال: Heart
سال: 1994
ISSN: 1355-6037
DOI: 10.1136/hrt.72.6_suppl.s52